ODBC Router is compatible with virtually all applications except those requiring the rare/exotic SQLExtendedFetch or Level 3-only features or 64-bit drivers. (Note that there are almost no Level-3 or 64-bit ODBC drivers available for Windows so consequently, there are few apps out there that require such features. ODBC Router itself runs fine on 64-bit Windows, Mac OS X and Linux using 32-bit apps and 32-bit drivers, just like Microsoft Office, etc...)